CBD, Pro-Inflammatory Markers, & Chronic Disease

CBD, Pro-Inflammatory Markers, & Chronic Disease

CBD and Pro-inflammatory Markers

Our body releases what are called cytokines when there are signs of infection, inflammation, trauma, or as a part of the immune response. The role cytokines play is to reduce inflammation and promote healing, but there are cytokines that act as proinflammatory, which increase negative inflammation and can make the disease process worse (Dinarello, 2000).

Understanding how to address chronic inflammation and reducing inflammatory markers is important for the overall health of mankind, especially when discussing chronic disease and cancer.

While inflammation is a normal response from the body, it is important to note that inflammation can make matters worse, specifically when discussing chronic disease. All chronic diseases have one thing in common and that is inflammation (Raghupathi, Raghupathi, 2018).

It is no secret that pro-inflammatory cytokines were associated with cardiovascular disease and oxidative stress, both which negatively affect our health (Stentz, Umpierrez, Cuervo, Kitabchi, 2004).

Chronic disease processes that are linked with states of chronic inflammation or elevated inflammatory markers include cancer, diabetes, high blood pressure (hypertension), heart disease (#1 killer in the world), respiratory diseases, arthritis, obesity, and oral diseases (Raghupathi, Raghupathi, 2018).

Almost half of all Americans suffer from one chronic disease, which makes it that much more important to show others a beneficial way to address it (Raghupathi, Raghupathi, 2018).

According to Cannabis and Cannabinoid Research, a peer reviewed journal, CBD + CBG + THC together were shown to significantly reduce proinflammatory markers and reduce inflammation systemically (Henshaw, Dewsbury, Lim, Steiner, 2021).

I believe it is important to educate those about the anti-inflammatory benefits that CBD has to offer, especially if they suffer from those chronic diseased states that were previously mentioned. Chronic disease is becoming a pandemic here in America and teaching others how to rely on something health promoting to address inflammation should be a priority! We owe it to humanity.

One of the finest herbs known to mankind if you ask me.

Bee Well,

Brandon Farless


Dinarello C. A. (2000). Proinflammatory cytokines. Chest118(2), 503–508. https://doi.org/10.1378/chest.118.2.503

Henshaw, F. R., Dewsbury, L. S., Lim, C. K., & Steiner, G. Z. (2021). The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review of In Vivo Studies. Cannabis and cannabinoid research6(3), 177–195. https://doi.org/10.1089/can.2020.0105

Raghupathi, W., & Raghupathi, V. (2018). An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach. International journal of environmental research and public health15(3), 431. https://doi.org/10.3390/ijerph15030431

Stentz, F. B., Umpierrez, G. E., Cuervo, R., & Kitabchi, A. E. (2004). Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises. Diabetes53(8), 2079–2086.https://doi.org/10.2337/diabetes.53.8.2079

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