CBD and Osteoarthritis

CBD and Osteoarthritis
What they tell you about osteoarthritis (OA):
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-OA is a degenerative joint disease that plays an enormous role in disability for many people around the world, affecting 25% of people over 18 around the world (Chen, et al., 2017).
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-OA affects the joints and cartlidge, making day to day activity painful and limits range of motion (Chen, et al., 2017).
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-OA affects the cartlidge, synovial joints, and bones, which are involved with the process of inflammation that comes along with OA (Chen, et al., 2017).
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-OA is a result of sports injuries, old age, genetic predisposition, obesity, and inflammation (Chen, et al., 2017).
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-There is no effective treatment for OA, damaged cartlidge, or damaged synovial membranes (Chen, et al., 2017).
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-Major symptoms include chronic pain, joint instability, joint stiffness, and joint space narrowing (Chen, et al., 2017).



What they donโ€™t tell you:
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-Topical CBD reduces the effects of pain and inflammation and has no side effects (Hammell et al., 2016).
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-Topical CBD bypasses first pass metabolism, making it very effective when absorbed transdermally (Hammell et al., 2016).
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-Transdermal CBD was shown to reduce joint swelling, thickening of the synovial membrane, and immune cell infiltration in rat models, which shows the immune modulating properties of CBD (Hammell et al., 2016).
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-CBD was shown to reduce the circumference of knee and joint swelling in rat models (Hammell et al., 2016).
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-CBD was shown to decrease pain, inflammation, and reduce in the secretion of pro-inflammatory markers (what causes inflammation), which is due to CBDโ€™s anti-inflammatory properties (Hammell et al., 2016).
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-The study concluded that transdermal CBD is being targeted as a treatment for OA and similar degenerative diseases (Hammell et al., 2016).
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These studies were from 2016, surely people with osteoarthritis are aware of this information, especially since there is no proven therapeutic treatment for addressing OAโ€ฆ.

No one cares more about your health than you do.

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*This information is for educational purposes only and simply sharing of the information pertained to this particular study. No medical claims or advice is being given.

References

Chen, D., Shen, J., Zhao, W., Wang, T., Han, L., Hamilton, J. L., & Im, H. J. (2017). Osteoarthritis: toward a comprehensive understanding of pathological mechanism. Bone research, 5, 16044. https://doi.org/10.1038/boneres.2016.44

Hammell, D. C., Zhang, L. P., Ma, F., Abshire, S. M., McIlwrath, S. L., Stinchcomb, A. L., & Westlund, K. N. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviors in a rat model of arthritis. European journal of pain (London, England), 20(6), 936โ€“948. https://doi.org/10.1002/ejp.818

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