Cannabinoids and Neuropathy?!
My goal is to help educate and share information so people can help themselves. After all, no one cares more about your health than you do…
So, let’s jump into it…
According to the Journal of Experimental Medicine, a peer reviewed medical journal, Neuropathic pain is a chronic pain condition which is difficult to treat and often certain medications for pain relief leave unwanted side effects leaving people to search for answers (Xiong, et al., 2012).
Neuropathy was stated to cause altered sensation, numbness, tingling, weakness, absent tendon reflexes, making neuropathy difficult to live with (Hughes, 2002). The problem is deterioration of the myelin sheaths that covers our nerves, leaving them exposed, causing many unwanted side effects and painful perception (Hughes, 2002).
This is where it gets interesting…
The Journal of Experimental Medicine stated that cannabinoids help give pain relieving effects, suppress chronic inflammation, and help deal with neuropathic pain (Xiong, et al., 2012). This may be due to the cannabinoid's interaction with the glycine receptors (GlyRs) in the central nervous system, which was stated to give people living with neuropathy hope and relief (Xiong, et al., 2012).
*This information is for educational purposes only and simply sharing of the information pertained to these particular studies. No medical advice or claims are being made.
Hughes R. A. (2002). Peripheral neuropathy. BMJ (Clinical research ed.), 324(7335), 466–469. https://doi.org/10.1136/bmj.324.7335.466
Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S. R., Willenbring, D., Guan, Y., Pan, H. L., Ren, K., Xu, Y., & Zhang, L. (2012). Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. The Journal of experimental medicine, 209(6), 1121–1134. https://doi.org/10.1084/jem.20120242