ADHD, An Imbalance With the ECS

ADHD, An Imbalance With the ECS



This topic is one that I struggle with personally and one of the reasons why I benefit from using our canna products. My ADHD is very distracting, keeping me from sitting still, studying, or completing even the simplest tasks. Because I have found help with cannabinoids like CBD and THC, it has dramatically improved my focus, helping me with reading, studying, and work. But why is that? There must be some explanation! Understanding the endocannabinoid system (ECS) and all that it regulates can give us a better understanding of this complex receptor system and how it  can help us improve how we face certain conditions, including ADHD. 


We know that the ECS is the most widespread receptor system in the human body. When we learn all that ECS modulates or controls, we get a better understanding of how we can use this system to address these imbalances at a cellular level because the ECS is the system that controls cell to cell communication and homeostasis (1). This means that we can activate this receptor in our cells using cannabinoids like CBD and THC to help restore balance. 


Our body makes endocannabinoids that help balance cellular signals, which is where we see the benefits of ADHD coming from. This is going to get a little technical and nerdy but stick with me till the end…


When we are dealing with ADHD, there is an imbalance of neurotransmitters that can cause difficulty focusing, difficulty completing tasks, organizing tasks, and sitting still, which can really hinder productivity at school and work. The ECS is the perfect receptor system to address an imbalance of neurotransmitters that is seen with ADHD because it can help restore the balance of neurotransmitters, check this out.


When there is too great of a flow of neurotransmitters (neuroexcitation) from the presynaptic cell, it causes a disturbance in the postsynaptic cell, which then causes an increase of calcium flowing into the postsynaptic cell, which is where our body makes endocannabinoids that fit like a key into this lock (receptor) (1).  The postsynaptic cell then sends the endocannabinoid key back to attach to the cannabinoid receptor (lock) on the presynaptic cell (1).  This lock and key mechanism triggers a chemical reaction in the presynaptic cell (where the neuroexcitation originally started), helping to downregulate the flow of neurotransmitter release, correcting the imbalance (1).  In short, cannabinoids can downregulate neuroexcitation, helping to restore balance for our cells, which directly addresses ADHD at a cellular level, essentially addressing the root cause of ADHD (1). SAY WHAT?!?! 


This is a breakthrough for science because we are actually addressing ADHD at a cellular level, but you won’t ever hear conventional medicine highlighting or sharing this information. Why you may ask? Because this addresses the root cause of ADHD, for which conventional medicine writes tons of prescriptions to manage the SYMPTOMS associated with ADHD. This means no money in their pocket, which is something big pharma don’t like. This is another example of big pharma suppressing information to take advantage of our health. There is no known medication out there that addresses imbalances associated with the endocannabinoid system. This plant is the only thing known to man to have that potential! The best part? It’s a natural plant.

As we can see, modulating or controlling the flow of neurotransmitters at a cellular level gives us more insight to understanding the “how” and “why” cannabinoids can help with ADHD and focus. This is because this complex receptor system (ECS) helps to regulate the flow of chemical messages that are being sent from cell to cell (which also explains how cannabinoids are an effective treatment for epilepsy), helping to maintain cellular homeostasis, especially when it comes to communication (2). 


This is a great example of how we can use this plant to target the underlying mechanism associated with ADHD, which should be the goal of ALL medical treatments (2). We want to address the root cause of whatever we are dealing with. Turns out that all we need to do to address ADHD is to control neurotransmitter release and how awesome is it that this plant can do that? 


Cheers to cannabinoid medicine and improving the quality of life of man, while simultaneously giving us health benefits.  


One amazing plant with seemingly endless uses, now that's what I call medicine!


Bee Well,

Brandon Farless


*This information is for educational purposes only and simply sharing information regarding these studies. No medical advice or claims are being made, by me anyway. 😊 Enjoy!




  1. Strohbeck-Kuehner, P., Mattern , R., & Skopp, G. (2008). (PDF) cannabis improves symptoms of ADHD - researchgate.
  2. Goldstein, B. (2020). Cannabis is medicine: How CBD and Medical Cannabis are healing everything from anxiety to chronic pain. Headline Home. 

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